Ctp biosynthetic process
CTP (cytidine triphosphate) synthetase catalyzes the last committed step in pyrimidine nucleotide biosynthesis: ATP + UTP + glutamine → ADP + Pi + CTP + glutamate It is the rate-limiting enzyme for the synthesis of cytosine nucleotides from both the de novo and uridine salvage pathways. The reaction proceeds by the … See more CTP synthase is an enzyme (EC 6.3.4.2) involved in pyrimidine biosynthesis that interconverts UTP and CTP. See more Active CTP synthase exists as a homotetrameric enzyme. At low enzyme concentrations and in the absence of ATP and UTP, CTP synthase exists as inactive monomer. As enzyme concentration increases, it polymerizes first to a dimer (such as the form … See more CTP synthase has been reported to form filaments in several different organisms. These include bacteria (C. crescentus), yeast ( See more • Pyrimidine biosynthesis See more Two isozymes with CTP synthase activity exist in humans, encoded by the following genes: • See more CTP synthase is precisely regulated by the intracellular concentrations of CTP and UTP, and both hCTPS1 and hCTPS2 have been seen to be maximally active at physiological concentrations of ATP, GTP, and glutamine. The activity of … See more Upregulated CTP synthase activity has been widely seen in human and rodent tumors. Mutations in the … See more WebInvolved in CTP biosynthetic process; phospholipid biosynthetic process; and pyrimidine nucleobase biosynthetic process. Located in cytoophidium. Human ortholog(s) of this …
Ctp biosynthetic process
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WebMar 21, 2024 · CTPS1 (CTP Synthase 1) is a Protein Coding gene. Diseases associated with CTPS1 include Immunodeficiency 24 and Nemaline Myopathy 7.Among its related pathways are Pyrimidine metabolism and UTP and CTP dephosphorylation II.Gene Ontology (GO) annotations related to this gene include hydrolase activity and CTP … WebGO:0044210 'de novo' CTP biosynthetic process Cellular Component: GO:0005829 cytosol: Descriptions from all associated GenBank mRNAs : AK025654 - Homo sapiens cDNA: FLJ22001 fis, clone HEP06629. BC034986 - Homo sapiens CTP synthase II, mRNA (cDNA clone MGC:32997 IMAGE:5268973), complete cds.
WebFunction. Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ( PubMed: 5793714 ). Required for repair of UV radiation- and etoposide-induced DNA damage ( PubMed: 18983998 ). WebCTP biosynthetic process Source:UniProtKB. 1 publication. Biological Process: glutamine metabolic process Source:UniProtKB-KW. Biological Process: nucleobase-containing compound metabolic process Source:ProtInc. 1 publication. Biological Process: pyrimidine nucleobase biosynthetic process Source:GO_Central.
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WebBiological Process: CTP biosynthetic process Source:GO_Central. 1 publication. Biological Process: glutamine metabolic process Source:UniProtKB-KW. Biological …
WebAnnotations Gene Ontology Term: CTP biosynthetic process GO ID GO:0006241 Aspect Biological Process Description The chemical reactions and pathways resulting in the … cherry red hoodiehttp://amigo.geneontology.org/amigo/term/GO:0006241 cherry red highlightsWebCTP synthase 1 là enzyme ở người được mã hóa bởi gen CTPS. Chức năng. Enzyme cytidine-5-prime-triphosphate synthetase xúc tác quá trình biến đổi uridine triphosphate (UTP) thành cytidine triphosphate (CTP). Enzyme này đóng vai ... flights mumbai to goa indiaWebCTP biosynthetic process. Ontology. biological_process. Synonyms. CTP anabolism, CTP biosynthesis, CTP formation, CTP synthesis. Alternate IDs. None. Definition. The … cherry red jordan shirtWebCtp synthase activity. Specific Function. This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent … cherry red honda civicWebA) These enzymes proceed via a covalent intermediate. B) Ammonia is released into a channel. C) Glutamate is a product of the reaction. D) ATP is needed to activate the glutamine. E) A Cys at the active site is critical for the activity of these enzymes. D) ATP is needed to activate the glutamine. cherry red highlights in brown hairWebJul 25, 2006 · CTP biosynthetic process Source:FlyBase. 1 publication. Biological Process: glutamine metabolic process Source:UniProtKB-KW. Biological Process: larval lymph gland hemopoiesis Source:FlyBase. 1 publication. Biological Process: pyrimidine nucleobase biosynthetic process Source:GO_Central. 1 publication. cherry red highlights on black hair